Abstract: Aluminum alloys have been widely used in structural engineering by virtue of light weight, high strength and good corrosion resistance, while their applications in frames are limited. In order to promote the application and development of aluminum alloy frames, researches are needed on the seismic behavior of aluminum alloy beam-to-column joints and frames. Thusly, engineering applications and researches on aluminum alloy beam-to-column joints and frames are reviewed. Elastoplastic pushover and time-history analyses on an aluminum alloy frame are carried out to evaluate its seismic performance. A reference is thusly provided for the further research, design, and application of aluminum alloy frames.