多级载荷耦合下的镍钛合金血管支架疲劳强度和寿命预测

张海潞; 冯海全; 王晓天; 王永刚

doi:10.6052/j.issn.1000-4750.2021.11.0862

多级载荷耦合下的镍钛合金血管支架疲劳强度和寿命预测

doi: 10.6052/j.issn.1000-4750.2021.11.0862

1.
内蒙古工业大学机械工程学院，内蒙古，呼和浩特 010051
2.
中国科学技术大学附属第一医院，安徽，合肥 230000
3.
苏州天鸿盛捷医疗器械有限公司，江苏，苏州 215000

基金项目: 国家自然科学基金项目(12162026)；内蒙古自治区科技计划项目(2020GG0024)

详细信息

作者简介:
张海潞(1997−)，女，河南人，硕士生，主要从事机械设计及理论研究(E-mail: 1520894585@qq.com)

王晓天(1967−)，男，安徽人，主任医师，学士，主要从事临床医学研究(E-mail: wangxiaotian@venmed.com)

王永刚(1969−)，男，江苏人，研究员，硕士，总经理，主要从事生物医学工程研究(E-mail: yonggang69@venmed.com)

通讯作者:
冯海全(1972−)，男，内蒙古人，教授，博士，博导，主要从事机械设计及理论研究(E-mail: fhq515@163.com)

中图分类号: R318.01
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- 被引次数: 0
出版历程
- 收稿日期: 2021-11-07
- 修回日期: 2022-03-04
- 网络出版日期: 2022-04-28
- 刊出日期: 2023-06-25

FATIGUE STRENGTH AND LIFE PREDICTION OF NITINOL STENT UNDER MULTI-LEVEL LOADS COUPLING

1.
College of Mechanical Engineering, Inner Mongolia University of Technology, Hohhot, Inner Mongolia 010051, China
2.
The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui 230000, China
3.
Suzhou Venmed Technology Co., Ltd, Suzhou, Jiangsu 215000, China

摘要

摘要: 为探究镍钛合金血管支架植入下肢动脉后产生断裂失效的原因，对Absolute Pro下肢动脉支架在多级载荷耦合作用下的疲劳性能进行研究。利用有限元方法对镍钛合金支架在一级(生理脉动、轴向拉伸、压缩、弯曲、扭转)、二级(拉-弯、拉-扭、压-弯、压-扭、弯-扭)和三级(拉-弯-扭、压-弯-扭)载荷下分别进行数值模拟，基于应变法评价支架的疲劳强度，采用名义应力法和断裂力学进行疲劳寿命预测。经疲劳性能分析发现，一级载荷和部分多级载荷下的支架疲劳强度均满足10年疲劳寿命的要求，其中二级载荷的拉-弯和三级载荷的拉-弯-扭下最大交变应变大于疲劳极限，易产生应力集中导致疲劳失效；寿命云图和安全系数显示，在一级载荷下，压缩载荷对支架寿命的影响最大，脉动载荷最小，在二级载荷下，拉-弯载荷影响最大，弯-扭载荷影响最小，在三级载荷下拉-弯-扭对支架寿命的影响大于压-弯-扭；基于断裂力学寿命预测发现，初始裂纹的大小对支架的寿命有显著的影响。该研究结果揭示了多级载荷对支架疲劳强度和寿命的影响，为支架的临床断裂失效机理提供理论参考。
- 血管支架 /
- 多级载荷 /
- 断裂力学 /
- 寿命预测 /
- 疲劳性能
Abstract: To explore the reason of fracture failure after Nitinol stent implantation in lower limb artery, the fatigue performance of Absolute Pro lower limb artery stent under multi-level load coupling was studied. The finite element method was used to simulate the Nitinol stent under primary (axial tensile, compression, bending, torsion, physiological pulsating cycle), secondary (tensile-bending, tensile-torsion, compression-bending, compression-torsion, bend-torsion) and third (tensile-bend-torsion, compression-bend-torsion) loads, The fatigue strength of the stent was evaluated by strain method, and the fatigue life was predicted by nominal stress method and fracture mechanics. The analysis of fatigue performance shows that the fatigue strength of the stent under the primary load and some multi-level loads can meet the requirements of 10-year fatigue life. The maximum alternate strains under the tension-bending of the second load and the tension-bending-torsion of the third load are greater than the fatigue limits, which leads to the stress concentration and fatigue failure; The life cloud diagram and safety factor show that the compressive load has the greatest influence on the stent life, and the physiological pulsating load is the smallest under the primary load; The tension-bending load has the greatest influence and the bending-torsion load has the least influence under the second load, and the tension-bending-torsion load has greater influence on the stent life than the compression-bending-torsion load under the third load. Based on fracture mechanics life prediction, it is found that the size of initial crack has a significant effect on the life of stent. The results reveal the influence of multi-level loads on the fatigue strength and life of stent, and provide theoretical reference for the clinical fracture failure mechanism of stents.
- vascular stent /
- multi-level loads /
- fracture mechanics /
- life prediction /
- fatigue performance

HTML全文

图 1 支架模型

Figure 1. Model of stent

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图 2 支架局部网格区域

Figure 2. Stent local mesh area

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图 3 支架植入图

Figure 3. Stent implantation diagram

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图 4 支架加载示意图

Figure 4. Stents loading diagram

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图 5 Absolute Pro支架在多级载荷下的疲劳极限图

Figure 5. Fatigue strength diagram of the Absolute Pro stents under multi-level loads

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图 6 支架多级载荷下的弹性应变分布云图

Figure 6. Elastic strain distribution cloud diagram of the Absolute Pro stents under multi-level loads

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图 7 Absolute Pro支架多级载荷下的寿命分布云图

Figure 7. Fatigue life distribution diagram of the Absolute Pro stents under multi-level loads

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图 8 支架在多级载荷下的安全系数

Figure 8. Safety factor of stent under multi-level loads

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图 9 支架在多级载荷下的断裂力学寿命值

Figure 9. Fracture mechanical life of stent under multi-level loads

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