Abstract: The multi-layered structure with porous materials is often applied in the blast/impact-resistant structures. The compound structure that porous aluminum is added to the middle of two steel plates can absorbs impact energy and relieves deformation of materials. To explore theory on the analysis of blast/impact-resistant structures, the material point method and nonlinear constitutive model are adopted to simulate large deformation and fracture of materials under impact load. MPM takes advantage of both Eurlerian and Lagrangian methods, and the material points is independent of mesh. Therefore, remeshing of FEM can be avoided, and coupling condition is automatically satisfied on interface of multiple materials. In this paper, a robust MPM simulation tool is developed and used to solve the response of compound blast/impact-resistant structure under explosion and impact load.