Abstract: Based on the degenerated shell theory, a finite element numerical model is proposed to analyze the behavior of the reinforced concrete slabs exposed to fire. The non-uniform temperature distribution across the section of the slab is considered. The temperature dependent thermal-elastic plastic material model is introduced in each layer through the layered model. The geometric nonlinearity due to large displacement is taken into consideration through Total Lagrange approach. The proposed model is validated by a fire experimental test on a reinforced concrete slab and the effects of parameters including the ratio of reinforcement and the thickness of the concrete cover are analyzed. The results show that the predictions agree well with the experimental results and the proposed model can be used to analyze the response of the reinforced concrete slabs under fire.