Abstract: A shaking table model test of structure-pile-soil interactions is accomplished on the transport hub of Tianjin station. The seismic response regulation of pile-soil is analyzed during the test. The analysis shows that in the process of wave spreading upward, a slight quake has an amplification effect to the peak acceleration, while the amplification coefficient reduces obviously in a big quake; meanwhile, the pile amplification coefficient is smaller than that of soil body, the existence of piles reduce the amplification coefficient; the strain of the pile in the middle part is larger than that of the two tips. With the seismic magnitude increasing, both the pile maximum displacement and the pile-soil contact pressure increase, the deformation becomes bigger as the pile’s height increases, and the contact pressure of the middle part increases significantly comparing with that of the two ends of the pile.