Abstract: Focuses on the design of compound, equipment development, process optimization and pipe quality evaluation for PVC (Polyvinyl chloride) pipes and safety evaluation, health monitoring and repair in PVC pipeline engineering. For more than 10 years, a series of breakthrough innovations have been achieved: High toughness compounds are obtained for large diameter PVC pipes, and the only automatic production line for large-diameter PVC pipes with a diameter of 1800 mm in China was established. The ABR pipe (made of acrylate polymer blended with poly (vinyl chloride) resin for water supply), a novel PVC pipe, is invented, which has high strength, high toughness and high impact resistance. The quality evaluation method of ABR pipe is established by carrying out the test of tensile, thermal expansion and bearing performance of ABR pipes under internal & external pressure. The safety evaluation method of large-diameter pipeline engineering under complex operating environment is established through prototype test and numerical simulation of the performance of buried PVC pipeline under natural disasters such as rockfall impact, soil collapse, landslide and geological fault. The fiber optic sensing technology is proposed for pipeline deformation health monitoring. Pipeline defects are located, identified and diagnosed by the combination of the 'Listening' robot, a pipeline inspection device, and an artificial intelligence algorithm for target detection. Four kinds of pipeline repair technology without excavation are proposed and applied to pipeline engineering repair. The safety of PVC pipeline project operation has been effectively guaranteed.