Abstract: The numerical simulation program of PFC2D (Particle Flow Code in 2 Dimension) particle flow based on the flow-solid coupling principle and, on its built-in FISHTANK function library and FISH language, defines the flow equation and pressure equation of fluid domain respectively, and carries out numerical simulation calculations on the diffusion process and, on the morphology and particle displacement of slurry during the slurry injection process. By adjusting the parameters of hist, n_bond, s_bond and measure in the PFC command flow, the tracking of granular body displacement changes is achieved, and the mesoscopic mechanism such as the diffusion law of soil slurry at different depths and the change of formation porosity is revealed. The numerical calculations show that: the grouting pressure has a significant effect on the alteration and destruction of the formation structure, and the fracturing effect becomes gradually worse with increasing adhesive strength, while the porosity increases significantly with increasing grouting pressure. Based on the elastic-plastic theory of the Mohr-Colomb criterion to theoretically derive the stress field of the soil around the borehole, it is pointed out that the mechanical mechanism of annular tension and radial compression is the fundamental reason for the appearance of fracturing grouting action mode. The increase of slurry viscosity is beneficial to improve the grouting effect of fracturing-compacting grouting, while the increase of friction coefficient has little effect on the grouting effect. The comparative analysis of the laboratory tests shows that the PFC2D simulation of the grouting process is feasible.