Abstract: Based on an auto-regressive model, the wind load time histories at different heights with return periods of one year, ten years and fifty years are simulated respectively and combined with earthquakes with different peak ground accelerations to study the performance of a 50-storey steel frame braced tube structure with pre-pressed spring self-centering energy dissipation (PS-SCED) braces. The results indicate that under the coupling action of earthquake and wind, the increase of wind load intensity has no significant effect on the interstorey drift ratio which is mainly influenced by earthquake intensity. As wind load intensity increases, the structural interstorey drift concentration factor decreases. As earthquake intensity decreases, wind load influences the structural base shear force more significantly. The difference between structural acceleration amplification coefficients under the coupling action of earthquake and wind and those solely under the earthquake is more significant with the increase of earthquake intensity. The PS-SCED braces dissipate energy sufficiently subjected to the coupling action of earthquake and wind to protect structure effectively, and the structural residual deformation is reduced obviously due to their excellent self-centering behavior.