Abstract: In order to investigate the mechanical performance of concrete-filled horizontal corrugated steel plate-tubular composite columns under bi-axial eccentric compression, two specimens were prepared for bi-axial eccentric loading test. Load versus deformation curves, failure mode and longitudinal strain were analyzed. A reasonable explanation of interaction between corrugated plate and steel tubes and concrete were proposed. Furthermore, a finite element analysis model was established. The influence of loading, the ductility and stiffness under different eccentricities, loading angles, thickness of the steel tubes and thickness of the corrugated plates were also analyzed. It is found that with the increase of the thickness of steel tubes, the bearing capacity of columns are improved evidently. And loading angles have barely influence on the bearing capacity. Finally, based on the bearing capacity calculation formula of steel-concrete composite columns in Eurocode 4, a calculation formula of the bearing capacity under bi-axial eccentric loading is proposed, which agrees well with the finite element results and is practical in actual engineering.