Abstract: The colloidal damper is a new type of vibration isolation material consisting of water and hydrophobic nano-porous particles. To perform modeling and mechanical analysis of the colloidal damper, a colloidal damper isolator was formed by sealing the colloidal damper into a compressible chamber. Quasi-static and dynamic loading experiments were conducted to investigate the hysteresis of colloidal damper isolators. A mechanical model with unknown parameters, including the cubic stiffness, viscous and Coulomb frictional damping, was established. Dynamic loading experiments were utilized to identify the unknown parameters. The vibration isolation performance of the colloidal damper was evaluated. The results show that the colloidal damper exhibited excellent low frequency vibration isolation properties and a strong damping effect. Therefore, it has a favorable application prospect as a damper for vibration reduction.