Abstract: The Beijing-Zhangjiakou High-speed Railway crossing a gas pipeline was an example to study the dynamic response of the gas pipeline structure to high-speed train loads. A 3D vehicle-track coupled dynamic model was built to calculate the loads. A 3D dynamic finite model for the protective rigid frame-soil-gas pipeline was built under the calculated loads. Comparing with the existing specifications, the assessment of the impact of the Beijing-Zhangjiakou High-speed Railway on the existing gas pipeline was carried out. The analysis results show that the frequency components of velocity and acceleration responses of the gas pipeline are mostly in the 0 Hz~10 Hz frequency band, which meets the criteria. The velocity and acceleration dynamic responses of the gas pipeline are increased with the increasing train speed. The dynamic effect of the train load with the design speed after the operation of the Beijing-Zhangjiakou High-speed Railway would not have a significant adverse effect on the gas pipeline under the U-shaped concrete rigid frame structure.