Abstract: The structural global overstrength factor is a global seismic performance factor. Six typical RC structures in high intensity regions are designed according to the current Chinese Codes, and finite element models are built based on OpenSees software. The objectivity and accuracy of modeling methods are verified by existing experimental results. The values and rules of overstrength factor are obtained by adaptive pushover analysis (POA) and incremental dynamic analysis (IDA). The analytical results show that infilled walls have a significant effect on the overstrength factor of RC frames. The effect of infilled walls on overstrength factors decreases gradually with the increase of structural height. The minimum overstrength factor of RC frames designed according to the current Chinese Codes is 1.2 when the seismic precautionary intensity is VIII. But considering the influence of infilled walls, the minimum overstrength factor becomes 2.1. Analysis methods have important effect on the overstrength factor. Comparing with dynamic analysis, static analysis underestimates overstrength factors.