Abstract: The bionics-based integrated analysis and design is performed for loading capacity and thermal protection of multilayer thin-walled structures through mechanical computations and optimization. The prototype of the thin multilayer model is inspired by the shell of snails that live on the floor of Indian Ocean. The layering model considering force and heat transfer is created and analyzed for characteristics of thermal protection and loading capacity. Through an example of three dimensional aerodynamic heating and a structural optimization based on genetic algorithm, it is demonstrated that the bionics-inspired multilayer structure has the best distribution of materials, and can be adopted as a superior prototype for the design of thermal protection and loading capacity.