Abstract: In this paper radial displacement and hoop stress of stenosed vessels are calculated based on the blood continuity equation, the blood motion equation, supposing that the blocking plaques and vessel wall are the same in their elastic properties, the vessel motion equation and the assumed blood pressure waveform function. The influence of the vessel stenosis’s variation on the deformation and stress of vessels is analyzed. The supporting forces of the stents implanted in vessels under different stenosis’s situation, and the corresponding radial displacement and hoop stress of vessels are obtained. The results in this paper can be adopted as a reference for the deformation and stress analysis of the stents implanted in stenosed vessels.