Abstract: The container vehicle-truss bridge coupled vibration inspired by the external environmental load greatly affects the automated container terminals’ (ACT) structural-safety and handling-efficiency. To solve this problem, firstly, the stochastic simulation of track irregularity and fluctuating wind time-history were generated, based on the numerical simulation method of a multidimensional homogeneous process. Then using a free-interface component mode-synthesis (CMS) method, the coupled vibration time-domain responses inspired by the self-excitation including track irregularity and hunting movement as well as wind and seismic load were obtained. Furthermore, the influences of wind load, seismic load etc. on the dynamic responses were studied. Finally, a miniature model test was designed to validate the simulation results. The following conclusions can be drawn: 1) the technique of applying free-interface CMS to solve a vehicle-bridge coupled-vibration problem is feasible. 2) The vehicle-bridge vertical vibration is caused mainly by the vehicle moving load, and the self-excitation is a major factor. Wind and seismic loads will greatly enhance the lateral vibration. As fluctuating wind mean velocity or vehicle velocity increases, the response increases too. And the sensitivity of the response to the seismic load is greater than that of the working-condition of wind load. 3) When vehicles are double-running, the maximal response is significantly greater than that due to single-running. Lead rubber bearing (LRB) can effectively reduce the acceleration response of both vehicle and bridge.