Abstract: For the characteristics of a large slenderness ratio, large flexibility and low damping of a cable-stayed bridge, the researches on the wind load and wind-induced vibration of stay cables are of a great engineering significance. Through a wind tunnel test, the wind-induced vibration performances of stay cables with special shape and size dent were studied. It was studied that the influence of wind angle of attack and Reynolds number on mean drag coefficient and mean lift coefficient of cables with dents. The influences of wind angle of attack and Reynolds number on characteristic of wind-induced vibration in the critical region of stay cables with dents were analyzed, the characteristics mainly including the amplitude and equilibrium position. It is shown that the wind angle of attack influences the profile of aerodynamic coefficients versus Reynolds number remarkably. For example, when the wind angle of attack is 30° or 60°, the critical number is smaller and the width of critical regime is bigger. There are obvious differences among maximum amplitudes with different wind angles of attack. With the wind angle of attack being 60°, the maximum amplitude is the maximum. And with the wind angle of attack being 30°, the maximum amplitude is the minimum. However, the maximum equilibrium position is basically the same at all wind angles of attack.