Abstract: With gas-liquid-solid three-phase flow as a research subject, the vibration responses induced by a coupled water hammer in a slurry reservoir-pipeline-valve system are obtained by combining the flux vector splitting method with a Lax-Wendroff scheme and an upwind Warming-Beam scheme. The influences of void fraction, density ratio, and elastic modulus ratio between the solid phase and liquid phase on vibration characteristics of the system are analyzed. The numerical results show that the velocities of pressure waves and stress waves decrease with the increase of void fraction, and the intensity of pressure fluctuation and pipe vibration fall simultaneously. As the density ratio between solid phase and liquid phase increases, the vibration of pipeline system becomes stronger, and additional vibration energy of the pipeline system mostly concentrates in the fluid, thus the pressure energy in the fluid rises rapidly. With increased elastic modulus ratio between solid phase and liquid phase, both pressure energy and vibration intensity in the pipeline system increase slightly. When the elastic modulus ratio between solid phase and liquid phase increases past a certain extent, its influence on the pressure energy and vibration intensity of the pipeline system can be neglected.