Abstract: Based on observed data of typhoons in Xiamen region during 1959- 2008, numerical simulation of typhoon is conducted using the Yan Meng wind-field model to obtain the extreme wind velocity series. Then, extreme wind velocity for different return periods is estimated and compared with the statistical results of the observed data of annual extreme wind velocity in Xiamen region, as well as the current structural code, to provide more accurate wind load information for the wind-resistant structural design. Furthermore, the effect of wind direction on extreme wind velocity is discussed in this paper to provide theoretical guidance of choosing appropriate building direction. Finally, gradient wind level as well as typhoon-governed wind profile in Xiamen region is proposed based on numerical simulation of the Yan Meng typhoon wind-field model.