Abstract: Taking BAI SHA Bridge in Guangzhou as an example, aerodynamic force on the bridge is simulated by CFX, and then, the static force coefficients of the arch section and main beam section are obtained under 3o, 0o and +3o attack angle. Comparing calculation results with experimental results from wind tunnel test, it is found: 1) the difference in the resist coefficient of arch section is 3.5%, 1.3% and 3.8% respectively under the three attack angles; 2) the difference in the static force coefficients of main beam is 4%, 2% and 3% respectively under 0o attack angle; 3) the difference in the resist coefficient and ascend coefficient is 0.1% and 0.6%. Therefore, aerodynamic force Coefficients of bridge section could be simulated accurately by CFD.