Abstract: In order to analyze the seismic behavior of high-rise precast concrete structures and develop guidelines for structural design, an experiment was conducted on precast layered slab and beam to column interior joints subjected to high axial loading and reversed cyclic loading with full-scale models, and the seismic performance was studied. The failure pattern, hysteretic characteristics, skeleton curve, displacement ductility, energy dissipation and effect of abutted seam were analyzed. The results indicated that the layered slab and the steel connection type for the beam have great influence on the seismic performance; Steel slippage appeared in the anchorage interior joint; Energy-dissipating capacity and the overall seismic performance of steel-through interior joint were almost equal to that of the monolithic joint.