Abstract: Based on the 527 slices of Aortic Dissection (AD) obtained by Computed Tomography (CT), the true lumen (TL) and the false lumen (FL) of Abdominal Aortic Dissection (AAD) were reconstructed by the medical processing software 3D-Doctor and reverse remodeling software Geomagic. The flow field characteristics of the true lumen and false lumen of AAD were calculated by Fluent. Some important physical quantities of the true lumen and false lumen such as shear stress, static pressure, and risk position of the wall were obtained. Using fluid dynamic software ANSYS-CFX, the interaction between the fluid and the wall, the deformation of the true lumen and the false lumen were also analyzed. The model was real, and the velocity and pressure boundary conditions were obtained by Magnetic Resonance Imaging (MRI). The results show that the wall shear stress becomes larger rapidly near the break point. The forward extension of FL increases faster than reverse extension. The deformation of the flexible wall is larger than that of the rigid wall, but the shear stress on the flexible wall is much smaller.