Abstract: The method for dynamic reliability analysis, in which the randomicity of dynamic loads and structural parameters can be considered,is proposed. Firstly, based on First Excursion Failure Criterion of random vibration and the performance function of random variables, the performance function of dynamic reliability is established. Then, Sequential Surface Response Method is used to fit the performance function. Finally, the reliability index is obtained through JC method. An example shows the method has high accuracy and efficiency. It has wide prospect of application especially in dynamic reliability analysis of complex engineering structures.