Abstract: In this paper, a unified expression mode of building case information is set up for structure scheme design, and 1008 highrise building cases are collected. A practical case database and its management system are developed by relational database, which includes the functions of data input, modification, erasion, inquiry, statistics and knowledge discovery, etc. With the actual intelligence form-selection of highrise buildings, the data-mining process and method based on the case-base quantification and fuzzy structure form-selection rule are addressed. In the meantime, the fuzzy interval division and its fuzzification method for quantitative attributes are set up and the potential application of Apriori algorithm -based association analysis method in intelligent building design is discussed. Based on the above results, new technical methods are presented to make full use of engineering knowledge information of practical case, and promote the efficiency, quality and intelligent standard of structure design.