Abstract: The present paper deals with the material parameter identification of orthotropic plate with a circular hole by the approach of integrating optimization and boundary element analysis. The material parameter identification problem is formulated into the problem of minimizing the objective function defined as a square sum of differences between the measured and calculated data on displacements. Levenberg-Marquardt method, in which sensitivity analysis is based on the differentiation of the discretized algebraic boundary element matrix equations, is used to solve the minimization problem. In the numerical example, the displacement results calculated by the boundary element method are compared with analytical results and the agreement between them is satisfactory. The proposed algorithm is used to identify the material parameters of orthotropic plate with a circular hole. Numerical example shows that the proposed method for parameter identification is feasible and effective.