Abstract: Concrete masonry walls subjected to blast loadings were analyzed with the explicit dynamic finite element method. The nonlinear material properties, nonlinear contact, large strain, large displacement were considered in the analysis model. The effects on high rise building caused by masonry wall deformation and failure under blast loadings were discussed. The loading time history on high rise building caused by masonry wall failure is presented. The numerical results show the mode of failure of masonry walls is significantly influenced by the strength of blast wave. The induced forces of structures are of triangle pattern, the larger the strength of blast wave, the higher the peak value of forces . The critical shear strength of mortar between masonry wall and the structural members played an important role on the moment of peak forces and the duration of forces.