Abstract: To ensure the operation safety for high-speed trains under non-synoptic winds such as tornadoes, rigid-model wind pressure measurements were conducted on a high-speed train on a viaduct in a tornado vortex simulator. We investigated the spatially varied aerodynamic load characteristics of the train under different locations of the tornado center and the effect of the wind screen on the wind loads. The results show that, compared to concrete railing, the wind screen reduces most unfavorable values of the total drag and lift force coefficients and the total overturning moment coefficients, but increases those of total pitching and yawing moment coefficients. The wind screen alters the mechanism of tornado vortices-train-viaduct interaction and therefore changes the most unfavorable location of the tornado center for total force coefficients. The influence of the height of the wind screen is different from each other for different components of total force coefficients.