Abstract: Based on the short-term wind speed data collected from temporary observation station at Puli Bridge site, the design wind speed for the bridge was estimated by applying block maximum model, peaks-over-threshold model, the method based on the dependence of wind speeds and virtual standard meteorological station method. In addition, the relationship between wind speed at the observation station and that at the reference point of bridge was determined by simulating the geomorphic characteristics in the region of the bridge site. Thus the design wind speed for various positions of the bridge deck can be obtained. Results show that there are some differences for design wind speeds calculated by various methods. The peaks-over-threshold model is advised to be adopted for short-term wind speed data. The wind speed of mountainous-valley bridge along the bridge axis is not uniform, hence it is not accurate in the wind-resistant design applying the constant terrain modification coefficient provided by the Bridge Design Specification. Accurate terrain modification coefficient should be obtained by numerical simulation method or wind tunnel test.