镍钛合金形状记忆效应和超弹性对不同结构特征下的医用自扩张支架的性能影响分析

INFLUENCE OF SHAPE MEMORY EFFECT AND SUPERELASTICITY OF NITINOL ALLOY ON THE PERFORMANCE OF SELF-EXPANDING MEDICAL STENT WITH DIFFERENT STRUCTURAL CHARACTERISTICS

  • 摘要: 目前介入医疗中使用的外周血管支架多为镍钛合金自膨胀支架,该支架可在病变血管区域实现自驱动扩张撑开病变血管,恢复其正常管腔结构与血流通道。该文主要基于以温度和应变为内变量的现象学本构模型及其用户自定义子程序UMAT,对负泊松比结构凹凸型自膨胀支架进行有限元仿真分析并与传统正泊松比结构V型支架自扩张过程进行机械性能的对比,包括支撑性能,轴向定位性能,应力-应变分布情况。结果表明:V型与凹凸型支架都能利用镍钛合金的超弹性和形状记忆效应成功实现自膨胀,且形状记忆效应能够有效减缓支架自扩张过程中的残余应力和应变;当支架自扩张时所处环境温度一样,镍钛合金两种材料特性对支架支撑性能影响是一致的;支架轴向缩短率主要受影响于支架的几何结构,与支架材料特性无关,随着自扩张的进行,V型支架轴向距离出现缩短现象(正泊松比效应),凹凸型支架轴向距离出现伸长现象(负泊松比效应)。该文为镍钛合金血管支架利用超弹性和形状记忆效应的装配过程提供了有效的理论模型和模拟方法。

     

    Abstract: Currently, the peripheral vascular stents used in interventional medicine are mainly self-expanding nitinol stents, which can autonomously expand at the lesion site to open the narrowed vessel, thereby restoring the normal lumen structure and blood flow. This study employs a phenomenological constitutive model incorporating the temperature and strain as internal variables, along with a user-defined subroutine UMAT, to conduct finite element simulation analysis of a concave-convex auxetic self-expanding stent with negative Poisson’s ratio. The mechanical performance of this stent is compared with that of a traditional V-shaped stent with positive Poisson’s ratio during self-expansion, in term of scaffolding capability, axial positioning stability, and stress-strain distribution. The results indicate that: Both the V-shaped and concave-convex stents successfully achieve self-expansion by leveraging the superelasticity and shape memory effect of nitinol, with the shape memory effect effectively mitigating the residual stress and strain during expansion; When the environmental temperature during self-expansion is the same, the influence of the two material properties of nitinol on the stent’s scaffolding performance is consistent; The axial shortening rate of the stent is primarily influenced by its geometric structure and is independent of the material properties. As the self-expansion proceeds, the V-shaped stent exhibits axial shortening (positive Poisson’s ratio effect), while the concave-convex stent demonstrates axial elongation (negative Poisson’s ratio effect). This study provides an effective theoretical model and simulation approach for the deployment process of nitinol vascular stents utilizing the superelasticity and shape memory effect.

     

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