Abstract: The static aeroelastic analysis of a large-aspect-ratio HIRENASD (High Reynolds Number Aero-Structural Dynamics) wing with Mach numbers between 0.4~1.6 is calculated, based on the one-way coupling method of computational fluid dynamics/computational structural dynamics (CFD/CSD). The aerodynamic characteristics of the wing are obtained by solving the three-dimensional N-S equations based on structured grids, the structural response of the wing under aerodynamic loads is analyzed, and the displacement and stress of the wing under fluid-structure coupling are obtained. The results show that the displacement of wing tip and the maximum stress of wing have a step change before and after the speed of sound, which can provide a corresponding reference for the design and analysis of relevant large aspect ratio wings.